Hydrolysis Of Vinyl Ethers

Enzymatic hydrolysis of the vinyl ether find read and cite all the research you need on researchgate.

Hydrolysis of vinyl ethers.

Direct synthesis of cyclic ketals of acetophenones by palladium catalyzed arylation of hydroxyalkyl vinyl ethers. With the aim of obtaining a new method to produce pva with a higher syndiotacticity than that produced by the traditional poly vinyl acetate hydrolysis. The journal of organic chemistry 1997 62 22 7858 7862. The two methods give identical rate constants.

The kinetics of the acid catalysed hydrolysis of ethyl vinyl ether in aqueous solution have been measured by following the disappearance of the ether and by following the appearance of acetaldehyde. From what i can tell you are having more trouble with the acidic hydrolysis of an enol ether to an aldehyde. The method has been used to convert an acyl indole into a vinyl ether in compounds related to the strychnos alkaloids. As has been pointed out by some comments your proposed mechanism is not really possible.

Hydrolysis of vinyl ether 3 c. Rates of hydrolysis of cis and trans β phenylvinyl methyl ethers cis and trans β p nitrophenyl vinyl methyl ethers and cis and trans β cyanovinyl ethyl ethers were measured in concentrated 10 55 wt aqueous perchloric acids. In this work the hydrolysis of some poly vinyl silyl ethers and poly vinyl ethers obtained by means of polymerization with a metallocene catalyst is reported. Vinyl s p 2 cations are very unstable and an s n 1 type dissociation of meoh is very unlikely.

Pdf on oct 1 1961 h r warner and others published the metabolism of plasmalogen. For the love of physics walter lewin may 16 2011 duration. Rates of hydrolysis of the vinyl ether functional groups of z and e β methoxyacrylic acid and z and e β methoxymethacrylic acid and their methyl esters were measured in aqueous perchloric acid solution additional rate measurements were also made for one substrate z β methoxymethacrylic acid in buffer solutions down to ph 7 and a rate profile was constructed. Since cyclopropanes 33 and fluorine 34 are of high interest in medicinal chemistry we wanted to see if our new compound class could be subjected to the convenient difluorocyclopropanation established by prakash et al.

Lectures by walter lewin. 35 to our delight we found that 3 m cleanly converts to the desired geminal difluorocyclopropane 7 m in good yield.